The U.S. National Guard soldiers undergoing training are tasked with delivering supplies to the secret scientific station “Sector 16” in the desert of New Mexico. Upon arrival, they discover that the station is deserted. When the squad detects a faint distress signal coming from a remote hill, Sergeant Jeffrey Millstone, the team leader, decides to organize a search and rescue mission. However, the soldiers have no idea that they are about to encounter a clan of cannibalistic mutants.