Miami police officers Marcus Burnett and Mike Lowrey learn from the news that their deceased police captain, Conrad Howard, is accused of corruption and ties to drug cartels. Marcus and Mike refuse to believe it, and soon receive a video from Howard himself, filmed before his death, in which he asks them to find his killers and clear his name. This is not so easy; now the hunt has been declared on Burnett and Lowrey themselves. The guys are forced to go on the run.